PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT4G25490.1
Common NameATCBF1, CBF1, DREB1B, ERF029, M7J2.140
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family ERF
Protein Properties Length: 213aa    MW: 23829.6 Da    PI: 4.7395
Description C-repeat/DRE binding factor 1
Gene Model
Gene Model ID Type Source Coding Sequence
AT4G25490.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP258.91.2e-184796255
          AP2  2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55
                  y+GVr++  +g+Wv+e+r+p   +k++r++lg+f tae+Aa+a++ a+++l+g
  AT4G25490.1 47 IYRGVRQRN-SGKWVSEVREP---NKKTRIWLGTFQTAEMAARAHDVAALALRG 96
                 69****999.7******9998...347*************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000181.83E-3446106No hitNo description
PfamPF008472.4E-134696IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.101.1E-3247106IPR001471AP2/ERF domain
PROSITE profilePS5103222.35247104IPR001471AP2/ERF domain
SMARTSM003802.6E-3347110IPR001471AP2/ERF domain
SuperFamilySSF541711.11E-2147106IPR016177DNA-binding domain
PRINTSPR003671.1E-94859IPR001471AP2/ERF domain
PRINTSPR003671.1E-97086IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009414Biological Processresponse to water deprivation
GO:0009631Biological Processcold acclimation
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000037anatomyshoot apex
PO:0000293anatomyguard cell
PO:0009005anatomyroot
PO:0009009anatomyplant embryo
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020100anatomyhypocotyl
PO:0001185developmental stageplant embryo globular stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 213 aa     Download sequence    Send to blast
MNSFSAFSEM FGSDYEPQGG DYCPTLATSC PKKPAGRKKF RETRHPIYRG VRQRNSGKWV  60
SEVREPNKKT RIWLGTFQTA EMAARAHDVA ALALRGRSAC LNFADSAWRL RIPESTCAKD  120
IQKAAAEAAL AFQDETCDTT TTNHGLDMEE TMVEAIYTPE QSEGAFYMDE ETMFGMPTLL  180
DNMAEGMLLP PPSVQWNHNY DGEGDGDVSL WSY
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1gcc_A6e-1448103359ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
3gcc_A7e-1448103662ATERF1
2gcc_A7e-1448103662ATERF1
Search in ModeBase
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO306869030.0
Genevisible254074_at0.0
Expression AtlasAT4G25490-
AtGenExpressAT4G25490-
ATTED-IIAT4G25490-
Functional Description ? help Back to Top
Source Description
TAIRTranscriptional activator that binds to the DRE/CRT regulatory element and induces COR (cold-regulated) gene expression increasing plant freezing tolerance. It encodes a member of the DREB subfamily A-1 of ERF/AP2 transcription factor family (CBF1). The protein contains one AP2 domain. There are six members in this subfamily, including CBF1, CBF2, and CBF3. This gene is involved in response to low temperature and abscisic acid.
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates cold-inducible transcription. CBF/DREB1 factors play a key role in freezing tolerance and cold acclimation. {ECO:0000269|PubMed:11798174, ECO:0000269|PubMed:16244146}.
Function -- GeneRIF ? help Back to Top
  1. We explored the regulation of CBF1-3 by the circadian clock.
    [PMID: 15728337]
  2. Ectopic expression of AtCBF1 was sufficient to significantly increase the freezing tolerance of non-acclimated leaves and stems relative to wild-type plants.
    [PMID: 17080948]
  3. CBF1 and CBF3, but not CBF2 have a concerted additive effect to induce the whole CBF regulon and the complete development of cold acclimation
    [PMID: 18093929]
  4. Transgenic expression of CBF1 in 2 Solanum species suggested an endogenous CBFpathway is involved in many of the alterations associated with cold acclimation.
    [PMID: 18182016]
  5. Data show that transgenic plants that constitutively express CBF1 accumulate less bioactive GA and as a consequence exhibit dwarfism and late flowering, and that DELLAs are components of the CBF1-mediated cold stress response.
    [PMID: 18757556]
  6. Important evolutionary changes in CBF1, -2, and -3 may have primarily occurred at the level of gene regulation as well as in protein function.
    [PMID: 18990244]
  7. SOC1 Directly Represses the Expression of CBF1 Genes.
    [PMID: 19825833]
  8. CBF1 domains bind to a target DNA motif with a universal CG step core recognition and different flanking bases preference
    [PMID: 19878300]
  9. The PKKPAGR sequence of CBF1 is essential for its transcriptional activity. Deletion of the sequence or mutations within it greatly impaired the ability of CBF1 to induce expression of its target genes.
    [PMID: 19948259]
  10. plays an important role in protection of PSII and PSI during the chilling stress under low irradiance
    [PMID: 20022137]
  11. Arabidopsis CBF1 gene provided protection and conferred cold tolerance to transgenic tomato without any phenotypic variation.
    [PMID: 21287175]
  12. SlERFs may act as intermediate transcription factors between AtCBF1 and pathogenesis-related (PR) genes via SlRAV in tomato, which results in enhanced tolerance to bacterial wilt.
    [PMID: 21398258]
  13. Studies indicate that DREB1A (CBF3), DREB1B (CBF1) and DREB1C (CBF2) play an important role in increasing stress tolerance.
    [PMID: 23271026]
  14. A major locus harboring three cold-responsive transcription factor genes CBF1, was identified.
    [PMID: 23721132]
  15. Jasmonate functions as a critical upstream signal of the ICE-CBF/DREB1 pathway to positively regulate Arabidopsis freezing tolerance.
    [PMID: 23933884]
  16. Transcriptional regulation of LUX by CBF1 mediates cold input to the circadian clock in Arabidopsis.
    [PMID: 24954045]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00454DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT4G25490.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By cold stress. {ECO:0000269|PubMed:9735350}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- ATRM (Manually Curated Upstream Regulators) ? help Back to Top
Source Upstream Regulator (A: Activate/R: Repress)
ATRM AT3G23250 (R), AT3G26744 (A), AT4G25470 (R), AT5G59820 (R), AT5G61270 (R)
Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source Target Gene (A: Activate/R: Repress)
ATRM AT1G02400(A), AT1G15550(A), AT1G20440(A), AT1G20630(A), AT1G43160(A), AT1G46768(A), AT2G34555(A), AT2G42540(A), AT3G50970(A), AT3G55610(A), AT5G15960(R), AT5G15970(A), AT5G17490(A), AT5G52310(A)
Regulation -- Hormone ? help Back to Top
Source Hormone
AHDsalicylic acid
Interaction ? help Back to Top
Source Intact With
IntActSearch P93835
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT4G25490
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB0077880.0AB007788.1 Arabidopsis thaliana mRNA for DREB1B, complete cds.
GenBankAB0138160.0AB013816.1 Arabidopsis thaliana gene for DREB1B, complete cds.
GenBankAL0221970.0AL022197.2 Arabidopsis thaliana DNA chromosome 4, P1 clone M7J2 (ESSA project).
GenBankAL0793500.0AL079350.1 Arabidopsis thaliana DNA chromosome 4, BAC clone T30C3 (ESSA project).
GenBankAL1615630.0AL161563.2 Arabidopsis thaliana DNA chromosome 4, contig fragment No. 63.
GenBankCP0026870.0CP002687.1 Arabidopsis thaliana chromosome 4 sequence.
GenBankFJ1692720.0FJ169272.1 Arabidopsis thaliana ecotype Spr1-2 DRE/CRT-binding factor 1 (CBF1/DREB1b) gene, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_567721.11e-162dehydration-responsive element-binding protein 1B
SwissprotP938351e-164DRE1B_ARATH; Dehydration-responsive element-binding protein 1B
TrEMBLB6DTR31e-162B6DTR3_ARATH; DRE/CRT-binding factor 1
TrEMBLB8Y6M81e-162B8Y6M8_OLIPU; CBF1
TrEMBLQ0Z7Z71e-162Q0Z7Z7_CUCSA; C-repeat/DRE binding factor 1
STRINGAT4G25490.11e-161(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM35528187
Representative plantOGRP6161718
Publications ? help Back to Top
  1. Lee H,Xiong L,Ishitani M,Stevenson B,Zhu JK
    Cold-regulated gene expression and freezing tolerance in an Arabidopsis thaliana mutant.
    Plant J., 1999. 17(3): p. 301-8
    [PMID:10097388]
  2. Knight H,Veale EL,Warren GJ,Knight MR
    The sfr6 mutation in Arabidopsis suppresses low-temperature induction of genes dependent on the CRT/DRE sequence motif.
    Plant Cell, 1999. 11(5): p. 875-86
    [PMID:10330472]
  3. Kanaya E,Nakajima N,Morikawa K,Okada K,Shimura Y
    Characterization of the transcriptional activator CBF1 from Arabidopsis thaliana. Evidence for cold denaturation in regions outside of the DNA binding domain.
    J. Biol. Chem., 1999. 274(23): p. 16068-76
    [PMID:10347158]
  4. Gilmour SJ,Sebolt AM,Salazar MP,Everard JD,Thomashow MF
    Overexpression of the Arabidopsis CBF3 transcriptional activator mimics multiple biochemical changes associated with cold acclimation.
    Plant Physiol., 2000. 124(4): p. 1854-65
    [PMID:11115899]
  5. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  6. Stockinger EJ,Mao Y,Regier MK,Triezenberg SJ,Thomashow MF
    Transcriptional adaptor and histone acetyltransferase proteins in Arabidopsis and their interactions with CBF1, a transcriptional activator involved in cold-regulated gene expression.
    Nucleic Acids Res., 2001. 29(7): p. 1524-33
    [PMID:11266554]
  7. Sakuma Y, et al.
    DNA-binding specificity of the ERF/AP2 domain of Arabidopsis DREBs, transcription factors involved in dehydration- and cold-inducible gene expression.
    Biochem. Biophys. Res. Commun., 2002. 290(3): p. 998-1009
    [PMID:11798174]
  8. Hao D,Yamasaki K,Sarai A,Ohme-Takagi M
    Determinants in the sequence specific binding of two plant transcription factors, CBF1 and NtERF2, to the DRE and GCC motifs.
    Biochemistry, 2002. 41(13): p. 4202-8
    [PMID:11914065]
  9. Liu J,Gilmour SJ,Thomashow MF,Van Nocker S
    Cold signalling associated with vernalization in Arabidopsis thaliana does not involve CBF1 or abscisic acid.
    Physiol Plant, 2002. 114(1): p. 125-134
    [PMID:11982943]
  10. Guo Y,Xiong L,Ishitani M,Zhu JK
    An Arabidopsis mutation in translation elongation factor 2 causes superinduction of CBF/DREB1 transcription factor genes but blocks the induction of their downstream targets under low temperatures.
    Proc. Natl. Acad. Sci. U.S.A., 2002. 99(11): p. 7786-91
    [PMID:12032361]
  11. Hsieh TH, et al.
    Heterology expression of the Arabidopsis C-repeat/dehydration response element binding factor 1 gene confers elevated tolerance to chilling and oxidative stresses in transgenic tomato.
    Plant Physiol., 2002. 129(3): p. 1086-94
    [PMID:12114563]
  12. Kim HJ,Kim YK,Park JY,Kim J
    Light signalling mediated by phytochrome plays an important role in cold-induced gene expression through the C-repeat/dehydration responsive element (C/DRE) in Arabidopsis thaliana.
    Plant J., 2002. 29(6): p. 693-704
    [PMID:12148528]
  13. Gong Z, et al.
    RNA helicase-like protein as an early regulator of transcription factors for plant chilling and freezing tolerance.
    Proc. Natl. Acad. Sci. U.S.A., 2002. 99(17): p. 11507-12
    [PMID:12165572]
  14. Fowler S,Thomashow MF
    Arabidopsis transcriptome profiling indicates that multiple regulatory pathways are activated during cold acclimation in addition to the CBF cold response pathway.
    Plant Cell, 2002. 14(8): p. 1675-90
    [PMID:12172015]
  15. Choi DW,Rodriguez EM,Close TJ
    Barley Cbf3 gene identification, expression pattern, and map location.
    Plant Physiol., 2002. 129(4): p. 1781-7
    [PMID:12177491]
  16. Hsieh TH,Lee JT,Charng YY,Chan MT
    Tomato plants ectopically expressing Arabidopsis CBF1 show enhanced resistance to water deficit stress.
    Plant Physiol., 2002. 130(2): p. 618-26
    [PMID:12376629]
  17. Haake V, et al.
    Transcription factor CBF4 is a regulator of drought adaptation in Arabidopsis.
    Plant Physiol., 2002. 130(2): p. 639-48
    [PMID:12376631]
  18. Dubouzet JG, et al.
    OsDREB genes in rice, Oryza sativa L., encode transcription activators that function in drought-, high-salt- and cold-responsive gene expression.
    Plant J., 2003. 33(4): p. 751-63
    [PMID:12609047]
  19. Shen YG, et al.
    An EREBP/AP2-type protein in Triticum aestivum was a DRE-binding transcription factor induced by cold, dehydration and ABA stress.
    Theor. Appl. Genet., 2003. 106(5): p. 923-30
    [PMID:12647068]
  20. Chinnusamy V, et al.
    ICE1: a regulator of cold-induced transcriptome and freezing tolerance in Arabidopsis.
    Genes Dev., 2003. 17(8): p. 1043-54
    [PMID:12672693]
  21. Boyce JM, et al.
    The sfr6 mutant of Arabidopsis is defective in transcriptional activation via CBF/DREB1 and DREB2 and shows sensitivity to osmotic stress.
    Plant J., 2003. 34(4): p. 395-406
    [PMID:12753580]
  22. Zarka DG,Vogel JT,Cook D,Thomashow MF
    Cold induction of Arabidopsis CBF genes involves multiple ICE (inducer of CBF expression) promoter elements and a cold-regulatory circuit that is desensitized by low temperature.
    Plant Physiol., 2003. 133(2): p. 910-8
    [PMID:14500791]
  23. Novillo F,Alonso JM,Ecker JR,Salinas J
    CBF2/DREB1C is a negative regulator of CBF1/DREB1B and CBF3/DREB1A expression and plays a central role in stress tolerance in Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A., 2004. 101(11): p. 3985-90
    [PMID:15004278]
  24. Zhang JZ,Creelman RA,Zhu JK
    From laboratory to field. Using information from Arabidopsis to engineer salt, cold, and drought tolerance in crops.
    Plant Physiol., 2004. 135(2): p. 615-21
    [PMID:15173567]
  25. Knight H,Zarka DG,Okamoto H,Thomashow MF,Knight MR
    Abscisic acid induces CBF gene transcription and subsequent induction of cold-regulated genes via the CRT promoter element.
    Plant Physiol., 2004. 135(3): p. 1710-7
    [PMID:15247382]
  26. Zhang X, et al.
    Freezing-sensitive tomato has a functional CBF cold response pathway, but a CBF regulon that differs from that of freezing-tolerant Arabidopsis.
    Plant J., 2004. 39(6): p. 905-19
    [PMID:15341633]
  27. Gilmour SJ,Fowler SG,Thomashow MF
    Arabidopsis transcriptional activators CBF1, CBF2, and CBF3 have matching functional activities.
    Plant Mol. Biol., 2004. 54(5): p. 767-81
    [PMID:15356394]
  28. Lee SC,Huh KW,An K,An G,Kim SR
    Ectopic expression of a cold-inducible transcription factor, CBF1/DREB1b, in transgenic rice (Oryza sativa L.).
    Mol. Cells, 2004. 18(1): p. 107-14
    [PMID:15359131]
  29. Cook D,Fowler S,Fiehn O,Thomashow MF
    A prominent role for the CBF cold response pathway in configuring the low-temperature metabolome of Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A., 2004. 101(42): p. 15243-8
    [PMID:15383661]
  30. Wang X, et al.
    Isolation and molecular characterization of a new CRT binding factor gene from Capsella bursa-pastoris.
    J. Biochem. Mol. Biol., 2004. 37(5): p. 538-45
    [PMID:15479616]
  31. Jackson MW,Stinchcombe JR,Korves TM,Schmitt J
    Costs and benefits of cold tolerance in transgenic Arabidopsis thaliana.
    Mol. Ecol., 2004. 13(11): p. 3609-15
    [PMID:15488017]
  32. Wang X, et al.
    Molecular cloning and characterization of a CBF gene from Capsella bursa-pastoris.
    DNA Seq., 2004. 15(3): p. 180-7
    [PMID:15497440]
  33. Vogel JT,Zarka DG,Van Buskirk HA,Fowler SG,Thomashow MF
    Roles of the CBF2 and ZAT12 transcription factors in configuring the low temperature transcriptome of Arabidopsis.
    Plant J., 2005. 41(2): p. 195-211
    [PMID:15634197]
  34. Fowler SG,Cook D,Thomashow MF
    Low temperature induction of Arabidopsis CBF1, 2, and 3 is gated by the circadian clock.
    Plant Physiol., 2005. 137(3): p. 961-8
    [PMID:15728337]
  35. Lee SC, et al.
    Characterization of an abiotic stress-inducible dehydrin gene, OsDhn1, in rice (Oryza sativa L.).
    Mol. Cells, 2005. 19(2): p. 212-8
    [PMID:15879704]
  36. Wang Z,Triezenberg SJ,Thomashow MF,Stockinger EJ
    Multiple hydrophobic motifs in Arabidopsis CBF1 COOH-terminus provide functional redundancy in trans-activation.
    Plant Mol. Biol., 2005. 58(4): p. 543-59
    [PMID:16021338]
  37. Cao S,Ye M,Jiang S
    Involvement of GIGANTEA gene in the regulation of the cold stress response in Arabidopsis.
    Plant Cell Rep., 2005. 24(11): p. 683-90
    [PMID:16231185]
  38. Alonso-Blanco C, et al.
    Genetic and molecular analyses of natural variation indicate CBF2 as a candidate gene for underlying a freezing tolerance quantitative trait locus in Arabidopsis.
    Plant Physiol., 2005. 139(3): p. 1304-12
    [PMID:16244146]
  39. Vergnolle C, et al.
    The cold-induced early activation of phospholipase C and D pathways determines the response of two distinct clusters of genes in Arabidopsis cell suspensions.
    Plant Physiol., 2005. 139(3): p. 1217-33
    [PMID:16258011]
  40. Nakano T,Suzuki K,Fujimura T,Shinshi H
    Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
    Plant Physiol., 2006. 140(2): p. 411-32
    [PMID:16407444]
  41. Zhao TJ, et al.
    Regulating the drought-responsive element (DRE)-mediated signaling pathway by synergic functions of trans-active and trans-inactive DRE binding factors in Brassica napus.
    J. Biol. Chem., 2006. 281(16): p. 10752-9
    [PMID:16497677]
  42. Mao Y,Pavangadkar KA,Thomashow MF,Triezenberg SJ
    Physical and functional interactions of Arabidopsis ADA2 transcriptional coactivator proteins with the acetyltransferase GCN5 and with the cold-induced transcription factor CBF1.
    Biochim. Biophys. Acta, 2006 Jan-Feb. 1759(1-2): p. 69-79
    [PMID:16603259]
  43. Benedict C,Geisler M,Trygg J,Huner N,Hurry V
    Consensus by democracy. Using meta-analyses of microarray and genomic data to model the cold acclimation signaling pathway in Arabidopsis.
    Plant Physiol., 2006. 141(4): p. 1219-32
    [PMID:16896234]
  44. Rajashekar CB,Zhou HE,Zhang Y,Li W,Wang X
    Suppression of phospholipase Dalpha1 induces freezing tolerance in Arabidopsis: response of cold-responsive genes and osmolyte accumulation.
    J. Plant Physiol., 2006. 163(9): p. 916-26
    [PMID:16949955]
  45. Benedict C, et al.
    The CBF1-dependent low temperature signalling pathway, regulon and increase in freeze tolerance are conserved in Populus spp.
    Plant Cell Environ., 2006. 29(7): p. 1259-72
    [PMID:17080948]
  46. D'Angelo C, et al.
    Alternative complex formation of the Ca-regulated protein kinase CIPK1 controls abscisic acid-dependent and independent stress responses in Arabidopsis.
    Plant J., 2006. 48(6): p. 857-72
    [PMID:17092313]
  47. Griffith M, et al.
    Thellungiella: an Arabidopsis-related model plant adapted to cold temperatures.
    Plant Cell Environ., 2007. 30(5): p. 529-38
    [PMID:17407531]
  48. Miura K, et al.
    SIZ1-mediated sumoylation of ICE1 controls CBF3/DREB1A expression and freezing tolerance in Arabidopsis.
    Plant Cell, 2007. 19(4): p. 1403-14
    [PMID:17416732]
  49. Pino MT, et al.
    Use of a stress inducible promoter to drive ectopic AtCBF expression improves potato freezing tolerance while minimizing negative effects on tuber yield.
    Plant Biotechnol. J., 2007. 5(5): p. 591-604
    [PMID:17559519]
  50. Franklin KA,Whitelam GC
    Light-quality regulation of freezing tolerance in Arabidopsis thaliana.
    Nat. Genet., 2007. 39(11): p. 1410-3
    [PMID:17965713]
  51. Chung S,Parish RW
    Combinatorial interactions of multiple cis-elements regulating the induction of the Arabidopsis XERO2 dehydrin gene by abscisic acid and cold.
    Plant J., 2008. 54(1): p. 15-29
    [PMID:18088305]
  52. Novillo F,Medina J,Salinas J
    Arabidopsis CBF1 and CBF3 have a different function than CBF2 in cold acclimation and define different gene classes in the CBF regulon.
    Proc. Natl. Acad. Sci. U.S.A., 2007. 104(52): p. 21002-7
    [PMID:18093929]
  53. Pino MT, et al.
    Ectopic AtCBF1 over-expression enhances freezing tolerance and induces cold acclimation-associated physiological modifications in potato.
    Plant Cell Environ., 2008. 31(4): p. 393-406
    [PMID:18182016]
  54. Pennycooke JC, et al.
    The low temperature-responsive, Solanum CBF1 genes maintain high identity in their upstream regions in a genomic environment undergoing gene duplications, deletions, and rearrangements.
    Plant Mol. Biol., 2008. 67(5): p. 483-97
    [PMID:18415686]
  55. Gutha LR,Reddy AR
    Rice DREB1B promoter shows distinct stress-specific responses, and the overexpression of cDNA in tobacco confers improved abiotic and biotic stress tolerance.
    Plant Mol. Biol., 2008. 68(6): p. 533-55
    [PMID:18754079]
  56. Achard P, et al.
    The cold-inducible CBF1 factor-dependent signaling pathway modulates the accumulation of the growth-repressing DELLA proteins via its effect on gibberellin metabolism.
    Plant Cell, 2008. 20(8): p. 2117-29
    [PMID:18757556]
  57. McKhann HI, et al.
    Natural variation in CBF gene sequence, gene expression and freezing tolerance in the Versailles core collection of Arabidopsis thaliana.
    BMC Plant Biol., 2008. 8: p. 105
    [PMID:18922165]
  58. Lin YH, et al.
    Molecular population genetics and gene expression analysis of duplicated CBF genes of Arabidopsis thaliana.
    BMC Plant Biol., 2008. 8: p. 111
    [PMID:18990244]
  59. Fursova OV,Pogorelko GV,Tarasov VA
    Identification of ICE2, a gene involved in cold acclimation which determines freezing tolerance in Arabidopsis thaliana.
    Gene, 2009. 429(1-2): p. 98-103
    [PMID:19026725]
  60. Eckardt NA
    CAMTA proteins: a direct link between calcium signals and cold acclimation?
    Plant Cell, 2009. 21(3): p. 697
    [PMID:19270185]
  61. Doherty CJ,Van Buskirk HA,Myers SJ,Thomashow MF
    Roles for Arabidopsis CAMTA transcription factors in cold-regulated gene expression and freezing tolerance.
    Plant Cell, 2009. 21(3): p. 972-84
    [PMID:19270186]
  62. Navarro M, et al.
    Complementary regulation of four Eucalyptus CBF genes under various cold conditions.
    J. Exp. Bot., 2009. 60(9): p. 2713-24
    [PMID:19457981]
  63. Wang S, et al.
    Molecular dynamics simulations reveal the disparity in specific recognition of GCC-box by AtERFs transcription factors super family in Arabidopsis.
    J. Mol. Recognit., 2009 Nov-Dec. 22(6): p. 474-9
    [PMID:19533627]
  64. Wang Y,Hua J
    A moderate decrease in temperature induces COR15a expression through the CBF signaling cascade and enhances freezing tolerance.
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